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HERDIN Record #: NCR-CSMC-17080909492638 Submitted: 09 August 2017 Modified: 05 January 2018

Comparison of MACCE outcomes in diabetic vs non-diabetic patients with left main Coronary Artery Disease.

Pierre Albert A. Alora,
Ariel Miranda

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BACKGROUND: Coronary artery bypass surgery is considered as the gold standard treatment of unprotected left main coronary artery (ULMCA) disease. However, rapid advances in percutaneous intervention (PCI) have made ULM-PCI a viable alternative.

OBJECTIVE: To compare the incidence of major adverse cardiovascular & cerebrovascular events (MACCE) among diabetic and non-diabetic patients with significant left main coronary artery disease treated with PCI.

METHODS: Cross sectional analytical study of elective Left Main Registry patients at the CSMC who underwent ULM-PCI from January 2007 to July 2014. Pearson's Chi-square was used to determine significant association between categorical variables.

RESULTS: There were 106 subjects (80% males) and ages ranged from 42 to 89 years old with a mean age of 65 years. The mean and longest follow-up was 4 and 7 years respectively. On follow-up, total MACCE was 13.2% (n=13) in diabetic and 5.7% (n=6) in non-diabetic based on p-0.1274. The total deaths between diabetic (n=6, 5.7%) was not significantly different from the non-diabetics (n=4, 3.8%) based on p-1.000. The proportion of revascularization between diabetics (n=7, 7.6%) is not significantly different from the non-diabetics (n=2, 1.9%) based on p-0.1084.There was also no significant difference in the incidence of stroke and myocardial infarction.

CONCLUSION: For patients with significant left main coronary artery disease, there was no significant difference between diabetic and non-diabetic patients with respect to major adverse cardiovascular and cerebrovascular diseases, total deaths, stroke, myocardial infarction and revascularization.

Publication Type
Book of Abstracts
Publication Sub Type
CSMC Research Abstract Compendium
LocationLocation CodeAvailable FormatAvailability
Cardinal Santos Medical Center - Research Center Abstract Print Format